The purpose of this study was to investigate the influence of Departmental Heads Managerial Skills on the implementation of School Programs, among secondary schools in Kakamega Central and East Districts. Objective of the study was to determine the level at which the Departmental Heads’ personnel Management skills influence the implementation of school programs. The study applied descriptive research design and the target population was 184 Heads of Departments (HoDs) in the selected schools and the sample selected were the Heads of Departments of schools. The respondents were selected through simple random and purposive sapling techniques. The research instruments used was a questionnaire which contained three parts; Open-ended questions that required them to give descriptive answers, closed ended questions that required a definite answer; and questions that tested them on their attitudes towards their roles as Departmental Heads in Secondary schools. The study findings revealed that majority of HODs did not receive adequate skills in personnel management to enable them run their departments effectively. It is recommended that the schools should organize training in leadership and school management